Effectiveness of an Unsupervised Online Yoga Program on Pain and Function in People With Knee Osteoarthritis: A Randomized Clinical Trial: Annals of Internal

Affiliations:

Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia (K.L.B., S.S., P.L.T., S.H., D.M., A.J.K., B.M., R.S.H.)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia (F.M.)

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, and Methods and Implementation Support for Clinical Health Research Hub, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia (K.E.L.)

Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia (D.J.H.).

Acknowledgment: The authors thank Associate Professor Romy Lauche and the expert panel (Maria Kirsten, Lisa Westlake, Therese Lew, Trish David, Margaret Clarke, and Elizabeth Nelson) for their involvement in the development and design of the yoga program; Lisa Westlake (instructor) and Shayne Milsom, Margaret Clarke, and Bob Gardner (group actors) for starring in the yoga videos; and Dr. Jessica Kasza for formulating the sample size and randomization schedule.

Grant Support: By a National Health and Medical Research Council Program Grant (#1091302) and the Centres of Research Excellence (#1079078).

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M22-1761.

Data Sharing Statement: The following data will be made available beginning 1 January 2023: deidentified participant data and data dictionary. We will share all data that support published results of the trial. Additional data that have not been published will be withheld until at least 6 months after publication. Data will be made available as required for specific, approved analyses and will be provided from a locked, cleaned, and deidentified study database. Requests will be reviewed by the principal investigator before approval. The following supporting documents will be made available beginning on 1 January 2023: statistical/analytic code and informed consent form (contact the principal investigator, Kim Bennell, at k.[email protected]edu.au). The investigators endorse the concept of data sharing to advance medical science. All requests for data sharing will be reviewed by the principal investigator to ensure no conflict with any planned subanalyses and to ensure that the data are shared in an ethical and protected manner. Analyses aimed at improving treatment of knee osteoarthritis for noncommercial purposes are eligible. Data will be made available after review and approval by the principal investigator. Before any analysis, a signed confidentiality agreement and/or data sharing agreement is required (restrictions: none).

Corresponding Author: Kim L. Bennell, PhD, Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia; e-mail, k.[email protected]edu.au.

Author Contributions: Conception and design: K.L. Bennell, R.S. Hinman, D.J. Hunter, S. Schwartz, P.L. Teo.

Analysis and interpretation of the data: K.L. Bennell, R.S. Hinman, D.J. Hunter, K.E. Lamb, F. McManus, B. Metcalf, P.L. Teo.

Drafting of the article: K.L. Bennell, A.J. Kimp, K.E. Lamb, B. Metcalf, P.L. Teo.

Critical revision for important intellectual content: K.L. Bennell, R.S. Hinman, D.J. Hunter, K.E. Lamb, F. McManus, B. Metcalf, P.L. Teo.

Final approval of the article: K.L. Bennell, S. Hawkins, R.S. Hinman, D.J. Hunter, A.J. Kimp, K.E. Lamb, D. Mackenzie, F. McManus, B. Metcalf, S. Schwartz, P.L. Teo.

Statistical expertise: K.E. Lamb, F. McManus.

Obtaining of funding: K.L. Bennell.

Administrative, technical, or logistic support: K.L. Bennell, S. Hawkins, A.J. Kimp, D. Mackenzie, B. Metcalf, S. Schwartz, P.L. Teo.

Collection and assembly of data: A.J. Kimp, B. Metcalf, S. Schwartz, P.L. Teo.

This article was published at Annals.org on 20 September 2022.

https://www.acpjournals.org/doi/10.7326/M22-1761