Testosterone, Serum (Female)

Testosterone is a male sex hormone produced in a woman’s ovaries in small amounts as well. Combined with estrogen, the female sex hormone, testosterone helps with the growth, maintenance, and repair of a woman’s reproductive tissues, bone mass, and human behaviors.

The normal ranges of testosterone levels for females are:

Age (in years)	Testosterone range (in nanograms per deciliter)
10–11	< 7–44
12–16	< 7–75
17–18	20–75
19+	8–60

• Hunter MH, et al. (2003). Evaluation and treatment of women with hirsutism.
  aafp.org/afp/2003/0615/p2565.html
• Mayo Clinic Staff. (2017). Congenital adrenal hyperplasia: Overview.
  mayoclinic.org/diseases-conditions/congenital-adrenal-hyperplasia/symptoms-causes/syc-20355205
• Mayo Clinic Staff. (2017). Polycystic ovary syndrome (PCOS): Symptoms and causes.
  mayoclinic.org/diseases-conditions/pcos/symptoms-causes/dxc-20342150
• Sowers MF, et al. (2001). Testosterone concentrations in women aged 25-50 years: Associations with lifestyle, body composition, and ovarian status. DOI:
  10.1093/aje/153.3.256
• Test ID: TTFB – testosterone, total, bioavailable, and free, serum. (n.d.).
  mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83686

What does it mean if your Testosterone, Serum (Female) result is too low?

Like estrogen and progesterone, testosterone normally declines with age. However, because women make testosterone in the ovaries and the adrenal glands, a low level of testosterone could indicate a problem with the function of either organ. Estrogen replacement therapy can also lower the level of testosterone.

If your testosterone level is low for your age and menstrual status, then you could be experiencing symptoms of low testosterone including:

– Decreased libido
– Muscle weakness
– Fatigue
– Depressed mood
– Weight gain

Testosterone also has some health-protective roles after menopause and low levels can increase some areas of health risk including:

– Bone loss/osteoporosis
– Muscle wasting/sarcopenia
– Obesity
– Depression
– Heart disease

Potential ways to increase testosterone:

There may also be some ways to boost testosterone naturally, including:

– eating a more balanced diet focused on fresh foods

Some foods can boost testosterone because they are high in certain vitamins or minerals, such as vitamin D or zinc, which are associated with increasing testosterone. The following foods can boost testosterone levels:

– Asparagus
– Beans (white/kidney/black)
– Pomegranate juice

Depending on your age, consider testosterone HRT or supplements that support low testosterone symptoms include Zinc, Maca, Tribulus, and Shatavari. If there are no symptoms of low testosterone, also carefully look at the 5a-metabolism and testosterone’s downstream metabolites, 5a-androstanediol and 5b-androstanediol to confirm a low androgenic state.

There is a very common genetic variant in this population that, if present, disallows much of testosterone from being converted into the water-soluble form found in urine. Actual testosterone levels, if this genetic variant is present, would be better assessed in a blood serum test (ideally total and free testosterone). This variant metabolism has no known clinical impact and impacts testosterone, 5a-DHT and 5b-androstanediol. It is not known to impact epi-testosterone, 5a-androstanediol or ther androgens as they are metabolized by a different enzyme.

If your testosterone level is very low (less than 1 ng per mg):

Androgens (DHEA and testosterone) in women help with muscle and weight maintenance, memory and brain function, mood, libido and a sense of wellbeing. If testosterone is very low, or low but without symptoms of androgen deficiency, it is best to test serum levels to confirm before starting a treatment program due to the potential of falsely low urinary testosterone. Lifestyle and diet modifications alone could be helpful to increase androgens such as:

– DHEA or TRT (testosterone replacement therapy) if appropriate and indicated.